Faculty

CUI Huanhuan
Research Assistant Professor
cuihh@sustc.edu.cn

Education Experience

2011.9-2016.4  Free University of Berlin        PhD

2008.9-2010.7  Northwest A&F University     Master

2004.9-2008.7  Northwest A&F University     Bachelor

 

Work Experience

2018.11-now         SUSTech           Research Assistant Professor

2017.9-2018.10     BGI Genomics       Genetic counsellor and senior lecturer

2015.10-2017.5     Charité – Universitätsmedizin Berlin Postdoc

 

Interdisciplinary Research Fields

1. Investigation of chromatin remodeling during development and diseases

2. Remodeling human diseases using pluripotent stem cells

 

Representative Publications

Cui H, Schlesinger J, Schoenhals S,Tönjes M, Dunkel I, Meierhofer D, Cano E, Schulz K, Berger MF, Haack T, Abdelilah-Seyfried S, Bulyk ML, Sauer S, Sperling SR. Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA. 2016. Nucleic Acids Research.

Cui H, Bansal V, Schulz K, Malecova B, Dall'Agnese A, Latella L, Gatto S, Chen W, Grunert M, Dorn C, Puri PL, and Sperling SR. Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation. 2017. Plos One.

Grunert M, Dorn C, Cui H, Dunkel I, Schulz K, Schoenhals S, Sun W, Berger F, Chen W, Sperling SR. DNA methylation alterations associated with gene expression changes depict congenital heart disease: Tetralogy of Fallot and ventricular septal defects. 2016. Cardiovascular Research.

Ben Jehuda R, Eisen B, Shemer Y, Mekies L.N, Szantai A, Reiter I, Cui H, Guan K, Haron-Khun S, Freimark D, Sperling S.R, Gherghiceanu M, Arad M, Binah O. CRISPR correction of the PRKAG2 gene mutation in the patient's iPSC-derived cardiomyocytes eliminates the electrophysiological and structural abnormalities. 2017. Heart Rhythm.