Our research is mainly focused on dissecting the molecular mechanisms of the intracellular protein and membrane trafficking in the secretory and vacuolar pathways of plant cells, and its roles in the biological processes including plant growth and development, cell differentiation, and interaction between plant and environment.
◆ Molecular mechanism of protein secretion
◆ Characterization of vacuolar trafficking pathway
◆ Molecular mechanism of seed storage protein transport
◆ Plant bioreactor
◆ 2012-present, Associate Professor, Department of Biology, Southern University of Science and Technology of China
◆ 2007-2012, Post-doctoral Fellow, The Chinese University of Hong Kong;
◆ 1998-2003, Assistant Researcher, Institute of Microbiology, CAS.
◆ Ph.D., in Biology, The Chinese University of Hong Kong, 2007;
◆ M.S., in Microbiology, Nankai University, 1998;
◆ B.S., in Biology, Nankai University, 1995.
Honors & Awards
◆ CUHK Postdoctoral Fellowship (2007)
1.Xin Ma,Zhen Chen,Dong Hua,Dongxu He,Linjun Wang,Peng Zhang,Junqi Wang, et. al. (2014) Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance.PNAS 111 (17), 6389-6394; doi:10.1073/pnas.1400272111.
2.Junqi Wang, Jinbo Shen, Yi Cai, David G. Robinson and LiwenJiang (2013) Successful transport to the vacuole of heterologously expressed mung bean 8S globulin occurs in seed but not in vegetative tissues. Journal of Experimental Botany64(6), 1587–1601.
3.TianranJia, Caiji Gao, Yong Cui, Junqi Wang, Yu Ding, Yi Cai, Takashi Ueda, Akihiko Nakano and Liwen Jiang (2013) ARA7(Q69L) expression in transgenic Arabidopsis cells induces the formation of enlarged multivesicular bodies.Journal of Experimental Botany 64 (10): 2817-2829.
4.Junqi Wang, Yu Chung Tse, GiselbertHinz, David G. Robinson and Liwen Jiang (2012) Storage globulins pass through the Golgi apparatus and multivesicular bodies in the absence of dense vesicle formation during early stages of cotyledon development in mung bean. Journal of Experimental Botany63(3), 1367-1380.
5.Yi Cai, Xiaohong Zhuang, Junqi Wang, Hao Wang, Sheung Kwan Lam, Caiji Gao, Xiangfeng Wang and Liwen Jiang (2012) Vacuolar degradation of two integral plasma membrane proteins, AtLRR84A and OsSCAMP1, is cargo ubiquitination-independent and prevacuolar compartment-mediated in plant cells. Traffic 13(7): 1023-1040.
6.Yu Ding, Juan Wang, Junqi Wang, York-Dieter Stierhof, David G. Robinson and Liwen Jiang (2012) Unconventional protein secretion. Trends in Plant Science17(10): 606-615.
7.Georgia Drakakaki, Wilhelmina van de Ven, Songqin Pan, Yansong Miao,Junqi Wang, Nana K Keinath, Brent Weatherly, Liwen Jiang, Karin Schumacher, Glenn Hicks and Natasha Raikhel (2012)Isolation and Proteomic Analysis of the SYP61 Compartment Reveals its Central Role in Exocytic Trafficking in Arabidopsis. Cell Research22: 413-424.
8.Yu Chung Tse, Junqi Wang and Liwen Jiang (2012) Multivesicular bodies in developing tobacco seed and mung bean are functionally equivalent. Plant Signaling & Behavior 7 (4): 450-453.
9.Yansong Miao, Hong-Ye Li, Jinbo Shen,Junqi Wang and Liwen Jiang (2011)QUASIMODO 3 (QUA3) is a putative homogalacturonan methyltransferase regulating cell wall biosynthesis in Arabidopsis suspension culture cells. Journal of Experimental Botany 62(14), 5063-5078.
10.Yun Shen,Junqi Wang, Yu Ding, Guillaume Gouzerh, Jean-Marc Neuhaus and Liwen Jiang (2011) The Rice RMR1 Defines a Novel Organelle as a Prevacuolar Compartment for the Protein Storage Vacuole Pathway. Molecular Plant4(5), 854-868.
11.Juan Wang#, Yu Ding#, Junqi Wang#(co-first author), Stefan Hillmer#, Yansong Miao, Sze Wan Lo, Xiangfeng Wang, David G. Robinson and Liwen Jiang (2010) EXPO: an Exocyst-positive Organelle distinct from Multivesicular Endosomes and Autophagosomes, mediates Cytosol to Cell Wall Exocytosis in Arabidopsis and Tobacco Cells. Plant Cell22, 4009-4030.
12.Hongjia Liu, Edward Lau, Maggie P. Y. Lam, Hung Chu, Sujuan Li, Guo Huang, Peng Guo, Junqi Wang, Liwen Jiang, Ivan K. Chu, Clive Lo and Yuezhi Tao (2010)OsNOA1⁄RIF1 is a functional homolog of AtNOA1⁄RIF1: implication for a highly conserved plant cGTPase essential for chloroplast function. New Phytologist 187(1), 83-105.
13.Junqi Wang, Yi Cai, Yansong Miao, Sheung Kwan Lam and Liwen Jiang (2009) Wortmannin induces homotypic fusion of plant prevacuolar compartments. Journal of Experimental Botany 60(11), 3075-3083.
14.Nan Xiao, Chuen Kam, Chong Shen, WenyingJin, Junqi Wang, Kwong Man Lee, Liwen Jiang and Jun Xia (2009) PICK1 deficiency causes male infertility in mice by disrupting acrosome formation. Journal of Clinical Investigation 119(4), 802-812.
15.Junqi Wang, Pui Kit Suen,Zeng-Fu Xu and Liwen Jiang (2009) A 64 kDa sucrose binding protein is membrane-associated and tonoplast-localized in developing mung bean seeds. Journal of Experimental Botany 60(2), 629-639.
16.Sheung Kwan Lam, Yu Chung Tse, Yansong Miao, Hong-Ye Li, Junqi Wang, Sze Wan Lo and Liwen Jiang (2007) Molecular characterization of plant prevacuolar and endosomal compartments. Journal of Integrative Plant Biology 49(8), 1119-1128.
17.Junqi Wang, Yubing Li, Sze Wan Lo, Stefan Hillmer, Samuel S.M. Sun, David G. Robinson and Liwen Jiang. (2007) Protein mobilization in germinating mung bean seeds involves vacuolar sorting receptors and multivesicular bodies. Plant Physiology 143, 1628-1639.
18.Junqi Wang, Yansong Miao and Liwen Jiang. (2006) Golgi-bypassing: delivery of biopharmaceutical proteins to protein storage vacuoles in plant bioreactors. Trends in Biotechnology 24(4), 147-149.