Faculty

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DENG Xingwang
Visiting Distinguished Professor (Long-Term)
US National Academy of Sciences member and American Association for Advancement of Science Fellow
deng@sustech.edu.cn

Self-introduction
Professor Xing Wang Deng was a Daniel C. Eaton Professor in Yale University. He got his Ph.D in University of California, Berkeley in 1989 and started his research group in Yale University in 1992 as an assistant professor. He was promoted associate professor in 1995, and full professor in 2001. His work has been reported in around 300 peer-reviewed publications, 14 in “Nature”, “Science” and “Cell” journals. Prof.Deng was awarded The Kumho Science International Award in 2003 and was elected as member of US National Academy of Sciences in 2013.

Research Interests
Professor Deng’s research is focused on light-mediated development in plants. Light is not only the major energy source, but also one of the essential environmental factors affecting the plant development throughout their life circle. COP/DET/FUS act as key repressors in photomorphogenesis. These proteins consist of 3 distinct E3 ligase complex and targets downstream substrates for ubiquitination and degradation, thereby repressing photomorphogenesis. We specifically focus on the following two areas:
1.Molecular mechanism of photomorphogenesis in plants
2.Molecular design breeding in crops

Educational background
1985.9-1989.4: Ph.D.,Department of Plant Biology, University of California, Berkeley
1982.9-1985.7: M.S.,Department of Biotechnology, School of Life Sciences, Peking University.
1978.9-1982.7: B.S.,Department of Biotechnology, School of Life Sciences, Peking University.

Professional experience
2016.07-present: Chair Professor, Department of Biology, SUSTech
2014.10-present: Dean, School of Advanced Agriculture Sciences and School of Life Sciences, Peking University.
2014.7.1-present: University Endowed Professor, School of Life Sciences, Peking University.
2000.7-2014.6.30: Cheung Kong Chair Professor,School of Life Sciences, Peking University.
2003.5-2014.6.30: Daniel C. Eaton Professor,Department of Molecular, Cellular, and Developmental Biology, Yale University.
2001.7-2014.6.30: Full Professor,Department of Molecular, Cellular, and Developmental Biology, Yale University.
2000.10-present: Director,Peking-Yale Joint Center for Plant Molecular Genetics and Agro-Biotechnology.
2003-2008: Co-Director,National Institute of Biological Sciences, Beijing, China
1998.7-2001.6: Associate Professor with tenure,Department of Molecular, Cellular, and Developmental Biology, Yale University.
1995.7-1998.6: Associate Professor with term,Department of Molecular, Cellular, and Developmental Biology, Yale University.
1992.1-1995.6: Assistant Professor, Department of Molecular, Cellular, and Developmental Biology, Yale University.
1989.5-1991.12:Postdoc,Department of Plant Biology, University of California, Berkeley

Honors & Awards
2013, Elected member of US National Academy of Sciences
2013, Elected fellow of American Association for Advancement of Science
2003, The Kumho Science International Award
1995, Presidential Faculty Fellow Award

Selected publications
1. Lin F., Xu D., Jiang Y., Chen H., Holm M., Fan L., and Deng X.W. (2017). Phosphorylation and negative regulation of CONSTITUTIVELY PHOTOMORPHOGENENICLY 1 in Arabidopsis. Proc. Natl. Acad. Sci. USA. 114:6617-6622.
2. Yang M., Wang X., Ren D., Huang H., Xu M., He G., and Deng X.W. (2017). Genomic architecture of biomass heterosis in Arabidopsis. Proc. Natl. Acad. Sci. USA 114:8101-8106.
3. Xu D., Jiang Y., Li J., Lin F., Holm M., and Deng X.W. (2016). BBX21, an Arabidopsis B-box protein, directly activates HY5 and is targeted by COP1 for 26S proteasome-mediated degradation. Proc. Natl. Acad. Sci. USA. 113:7655-7660.
4. Li K., Yu R., Fan L.M., Wei N., Chen H. and Deng X.W. (2016). DELLA-mediated PIF degradation contributes to coordination of light and gibberellin signalling in Arabidopsis. Nat Commun. 7:11868.
5. Yang L., Li B., Zheng X.Y., Li J., Yang M., Dong X., He G., An C., and Deng X.W. (2015). Salicylic acid biosynthesis is enhanced and contributes to increased biotrophic pathogen resistance in Arabidopsis hybrids. Nat Commun. 6:7309.
6. Chen F., Li B., Demone J., Charron J.B., Shi X., and Deng X.W. (2014). Photoreceptor partner FHY1 has an independent role in gene modulation and plant development under far-red light. Proc. Natl. Acad. Sci USA.111:11888-11893.
7. Xu D., Lin F., Jiang Y., Huang X., Li J., Ling J., Hettiarachchi C., Tellgren-Roth C., Holm M., and Deng X.W. (2014). The RING-Finger E3 ubiquitin ligase COP1 SUPPRESSOR1 negatively regulates COP1 abundance in maintaining COP1 homeostasis in dark-grown Arabidopsis seedlings. Plant Cell 26:1981-1991.