MA dawei
Chair Professor
Chinese Academy of Science and Engineering

Dr. Dawei Ma received his PhD in 1989 from Shanghai Institute of Organic Chemistry (SIOC), and did his postdoctoral studies at the University of Pittsburgh and Mayo Clinic. He returned to SIOC in 1994, and was appointed as research professor in 1995. His research interests currently focus on the development of new synthetic methodologies, the total synthesis of complex natural products and their SAR and action mode studies, as well as the discovery of small modulators for target proteins and special biological processes.





1. Total Synthesis of Leucosceptroids A and B, Sheng Guo, Jie Liu, Dawei Ma, Angew. Chem. Int. Ed. 2015, 54, 1298.


2. Intramolecular dearomative oxidative coupling of indoles: A unified strategy for the total synthesis of indoline alkaloid, Weiwei Zi, Zhiwei Zuo, Dawei Ma, Acc. Chem. Res. 2015, 48, 702.


3. CuI/Oxalic Diamides Catalyzed Coupling Reaction of (Hetero)Aryl Chlorides and Amines, Wei Zhou, Mengyang Fan, Junli Yin, Yongwen Jiang, Dawei Ma, J. Am. Chem. Soc. 2015, 137, 11942.


4. Rhodium-Catalyzed Regioselective C7-Functionalization of N-Pivaloyl Indoles, Lanting Xu, Chao Zhang, Yupeng He, Lushi Tan, Dawei Ma, Angew. Chem. Int. Ed. 2016, 55, 321.


5. Diaryl Ether Formation through CuI/Oxalic Diamide Catalyzed Coupling of (Hetero)aryl Chlorides and Phenols, Mengyang Fan, Wei Zhou, Yongwen Jiang, Dawei Ma, Angew. Chem. Int. Ed. 2016, 55, 6211.


6. Copper-Catalyzed Hydroxylation of (Hetero)aryl Halides under Mild Conditions, Shanghua Xia, Lu Gan, Kailiang Wang, Zheng Li, Dawei Ma, J. Am. Chem. Soc. 2016, 138, 13492.


7. Convergent route to ent-Kaurane diterpenoids: Total synthesis of Lungshengenin D and 1a,6a-Diacetoxy-ent-kaura-9(11),16-dien-12,15-dione. Xiangbo Zhao, Wu Li, Junjie Wang, Dawei Ma*, J. Am. Chem. Soc., 2017, 139, 2932-2935.


8. Selected copper-based reactions for C-N, C-O, C-S and C-C bond formation. Subhajit Bhunia, Govind Goroba Pawar, S. Vijay Kumar, Yongwen Jiang, Dawei Ma*, Angew. Chem. Int. Ed., 2017, 56, 16136-16179.


9. Divergent entry to gelsedine-type alkaloids: total syntheses of (-)-Gelsedilam, (-)-Gelsenicine, (-)-Gelsedine, and (-)-Gelsemoxonine. Pingluan Wang, Yang Gao, Dawei Ma*, J. Am. Chem. Soc., 2018, 140, 11608-11612.


10. Thiourea-catalyzed asymmetric michael addition of carbazolones to 2-chloroacrylonitrile: total synthesis of 5,22-Dioxokopsane, Kopsinidine C, and Demethoxycarbonylkopsin. Dongshun Ni, Yi Wei, Dawei Ma*, Angew. Chem. Int. Ed., 2018, 57, 10207 -10211.


11. A unified approach for the assembly of atisine- and hetidine-type diterpenoid alkaloids: total syntheses of azitine and the proposed structure of Navirine C. Jie Liu, Dawei Ma*, Angew. Chem. Int. Ed., 2018, 57, 6676 -6680.


12. Oxalic Diamides and tert-Butoxide: Two Types of Ligands Enabling Practical Access to Alkyl Aryl Ethers via Cu-Catalyzed Coupling Reaction, Zhixiang Chen, Yongwen Jiang, Li Zhang, Yinlong Guo, Dawei Ma*, J. Am. Chem. Soc. 2019, 141, 3541–3549.


13. A Scalable Total Synthesis of the Antitumor Agents Et-743 and Lurbinectedin, Weiming He, Zhigao Zhang, Dawei Ma*, Angew. Chem. Int. Ed. 2019, 58, 3972-3976.


14. Total Synthesis of Kopsinitarine E, Karre Nagaraju, Dongshun Ni, Dawei Ma, Angew. Chem. Int. Ed. 2020, 59, 22039-22042.


15. In Pursuit of Synthetic Efficiency: Convergent Approaches, Yang Gao, Dawei Ma, Acc. Chem. Res. 2021, 54, 569-582.


16. Assembly of a-(Hetero)aryl Nitriles via Copper-Catalyzed Coupling Reactions with (Hetero)aryl Chlorides and Bromides, Chen, Y.; Xu, L.; Jiang, Y.; Ma, D. Angew. Chem. Int. Ed. 2021, 60, 7082-7086