LIU Chuang
Research Associate Professor

Research Interests

◆Structure study of the skeletal/cardiac muscle Excitation-Contraction coupling.

In vivo structure determination of mitochondria in chronic/acute heart disease cells.

◆Helical structure determination of biological assemblies.


Professional Experience

◆ 2018-Now SUSTech              Research associate professor

◆ 2016-2018 ShanghaiTech          Director of Cryo-EM

◆ 2013-2016 University of Pittsburgh  Postdoc


Educational Background

◆ 2013  Peking University   Ph.D       Biophysics

◆ 2009  Peking University   M.S        Biophysics

◆ 2006  Nankai University   B.S        Physics


Selected Publication

  1. Liu C., Fan G., Wang Z., Chen H., Yin C., (2017) Allosteric conformational changes of human HBV core protein transform its assembly., Scientific Reports, DOI: 10.1038/s41598-017-01568-9.
  2. Liu C., Perilla J., Ning J., Lu M., Hou G., Ramalho R., Himes B., Zhao G., Bedwell G., Byeon I., Ahn J., Gronenborn A., Prevelige P., Rousso I, Polenova T., Schulten K., Zhang P. (2016) Cyclophilin A Stabilizes HIV-1 Capsid through a Novel Non-canonical Binding Site. Nature Communications: 7:10714, DOI:10.1038
  3. Tillman T.S., Alvarez F.J., Reinert N.J., Liu C., Wang D., Xu Y., Xiao K., Zhang P. and Tang P. (2016) Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from E. coli. J Biol Chem. Pii: jbc.M116.729970.
  4. Lu J, Liu C, Wang P, Ghazwani M, Xu J, Ma X, Zhang P, Li S., (2015) The self-assembling camptothecin-tocopherol prodrug: An effective approach for formulating camptothecin. Biomaterials. Sep: 62:176-87
  5. Zhang K. Ezemaduka A., Wang Z.,Hu H., Shi X., Liu C., Lu X., Fu X., Chang Z.& Yin C.,(2015),A Novel Mechanism for Small Heat Shock Proteins to Function as Molecular Chaperones; Scientific Reports:8811

6.  Saini S.G., Liu C., Zhang P. and Lee T.H. (2014). Membrane Tethering by the Atlastin GTPase Depends on GTP  Hydrolysis But Not on Forming the crossover Configuration.Mol Biol Cell 25(24):3942-53