个人简介：

崔欢欢，2016年博士毕业于柏林自由大学生物学专业，2018年12月加入南方科技大学，历任研究助理教授、研究副教授，硕士生导师。主要研究方向为基因转录和表观遗传调控的机制研究和方法开发，RNA翻译的顺式调控元件和反式作用因子的鉴定与功能分析。

研究领域：

基因转录与表观遗传；

RNA翻译调控。

工作经历：

2018.12 至今，南方科技大学；

2017.09– 2018.11，临床科研经理，深圳华大基因股份有限公司；

2016.05 – 2017.06，博士后，柏林夏洛蒂医科大学；

2010.09 – 2011.08，柏林洪堡大学，研究助理。

学习经历：

2011.09 – 2016.04，柏林自由大学，生物学，博士；

2004.09 – 2010.06，西北农林科技大学，国家生命科学基地班，本硕。

代表文章： 

1. Cui H, Yi H, Bao H, Tan Y, Tian C, Shi X, Gan D, Zhang B, Liang W, Chen R, Zhu Q, Fang L, Gao X, Huang H, Tian R, Sperling SR, Hu Y, Chen W (2022) The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling. Nature Communications.

2. Yang C, Liu Y, Hu Y, Fang L, Huang Z, Cui H, Xie J, Hong Y, Chen W, Xiao N, Li Q, Liu W-H, Xiao C (2022) Myc inhibition tips the immune balance to promote antitumor immunity. Cellular & Molecular Immunology.

3. Tian S, Zhang B, He Y, Sun Z, Li J, Li Y, Yi H, Zhao Y, Zou X, Li Y, Cui H, Fang L, Gao X, Hu Y, Chen W (2022) CRISPR-iPAS: a novel dCAS13-based method for alternative polyadenylation interference. Nucleic Acids Res.

4. Sun T, Zhang Z, Tian L, Zheng Y, Wu L, Guo Y, Li X, Li Y, Shen H, Lai Y, Liu J, Cui H, He S, Ren Y, Yang G (2022) Dualistic classification of high grade serous ovarian carcinoma has its root in spatial heterogeneity. J Adv Res.

5. Zhou J, Zhang B, Li H, Zhou L, Li Z, Long Y, Han W, Wang M, Cui H, Li J, Chen W, Gao X (2022) Annotating TSSs in Multiple Cell Types Based on DNA Sequence and RNA-seq Data via DeeReCT-TSS. Genomics Proteomics Bioinformatics.

6. Fang L, Li G, Sun Z, Zhu Q, Cui H, Li Y, Zhang J, Liang W, Wei W, Hu Y, Chen W (2021) CASB: a concanavalin A-based sample barcoding strategy for single-cell sequencing. Mol Syst Biol.

7. Yi H, Li G, Long Y, Liang W, Cui H, Zhang B, Tan Y, Li Y, Shen L, Deng D, Tang Y, Mao C, Tian S, Cai Y, Zhu Q, Hu Y, Chen W, Fang L (2020) Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT. Oncogene.

8. Fang L, Wang W, Li G, Zhang L, Li J, Gan D, Yang J, Tang Y, Ding Z, Zhang M, Zhang W, Deng D, Song Z, Zhu Q, Cui H, Hu Y, Chen W (2020) CIGAR-seq, a CRISPR/Cas-based method for unbiased screening of novel mRNA modification regulators. Mol Syst Biol.

9. Cui H, Schlesinger J, Schoenhals S, Tonjes M, Dunkel I, Meierhofer D, Cano E, Schulz K, Berger MF, Haack T, Abdelilah-Seyfried S, Bulyk ML, Sauer S, Sperling SR (2016) Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA. Nucleic Acids Res.

10. Cui H, Bansal V, Grunert M, Malecova B, Dall'Agnese A, Latella L, Gatto S, Ryan T, Schulz K, Chen W, Dorn C, Puri PL, Sperling SR (2017) Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation. PLoS One.

11. Grunert M, Dorn C, Cui H, Dunkel I, Schulz K, Schoenhals S, Sun W, Berger F, Chen W, Sperling SR (2016) Comparative DNA methylation and gene expression analysis identifies novel genes for structural congenital heart diseases. Cardiovasc Res.

12. Ben Jehuda R, Eisen B, Shemer Y, Mekies LN, Szantai A, Reiter I, Cui H, Guan K, Haron-Khun S, Freimark D, Sperling SR, Gherghiceanu M, Arad M, Binah O (2018) CRISPR correction of the PRKAG2 gene mutation in the patient's induced pluripotent stem cell-derived cardiomyocytes eliminates electrophysiological and structural abnormalities. Heart Rhythm.