师资

郭晨
研究助理教授
guoc@sustech.edu.cn

研究领域:
◆胰岛因子在胃肠道肿瘤中的作用及其分子机制研究;
◆细胞黏附蛋白在肾脏发育及相关疾病中的分子机制研究

工作经历:
2018-至今 南方科技大学生物系 研究助理教授
2015-2017 复旦大学(南方科技大学联合培养),博士后

学习经历:
2015年,北京大学医学部生物化学与分子生物学,获博士学位
2012年,韩国全南大学校,获硕士学位
2010年,大连大学生物工程学系,获学士学位

代表文章:
1. Chen Guo, Guan Li, Jianing Hou, Xingming Deng, Sheng Ao, Zhuofei Li, Guoqing Lyu. Tumor pyruvate kinase M2: A promising molecular target of gastrointestinal cancer. Chin J Cancer Res. 2018 Dec; doi: 10.21147/j.issn.1000-9604.2018.06.11
2. Sun Y#*, Guo C#, Ma P, Lai Y, Yang F, Cai J, Sheng Y, Cheng Z, Tian R, Deng Y, Xiao G*, Wu C*. Kindlin-2 association with RhoGDIα suppresses Rac1 activation and podocyte injury. J Am Soc Nephrol. 2017 Aug 3; pii: ASN.2016091021.
3. Guo Chen, Jianing Hou, Sheng Ao, Xingming Deng, Guoqing Lyu: HOXC10 up-regulation promotes gastric cancer cell proliferation and metastasis through MAPK pathway. Chin J Cancer Res. 2017 Dec;29(6):572-580. doi: 10.21147/j.issn.1000-9604.2017.06.12.
4. Wang Yang, Li Yuejiao, Guo Chen, Lu Qin, Wang Wweiping, Jia Zhuqing, Chen Ping, Ma Kangtao, Reinberg D, Zhou Chunyan*: ISL1 and JMJD3 synergistically control cardiac differentiation of embryonic stem cells. Nucleic Acids Res. 2016 Aug 19;44(14):6741-55.
5. Guo Chen, Wang Weiping, Shi Qiong, Chen Ping, Zhou Chunyan*:Abnormally expressed ISL-1 represents a potential prognostic factor in gastric cancer. Hum Pathol. 2015 Sep;46(9):1282-9.
6. Hong Chang-Soo, Oh Jeong, Piao Zhengri, Guo Chen, Jung Mi-Ran, Choi Chan, Park Young-Kyu*: HOXB5 induces invasion and migration through direct transcriptional upregulation of B-catenin in human gastric carcinoma. Biochemical Journal. 2015 Dec 15;472(3):393-403.
7. Zhang Qiao, Yang Zhe, Jia Zhuqing, Liu Cuiling, Guo Chen, Lu Huafei, Chen Ping, Ma Kangtao, Wang Weipinh, Zhou Chunyan*: ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex. Molecular cancer 2014, 13:181.

联系方式:
深圳市南山区西丽学苑大道1088号南方科技大学生物楼402室
邮编:518055
电子邮件:guoc@sustech.edu.cn

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