师资

杨用
研究副教授
yangy9@sustech.edu.cn

研究兴趣:
1. 生化分析与分子诊断;
2. 抗菌新策略及抗菌机理研究。

 

教育背景:
2003-2009,中国科学技术大学, 博士(细胞生物学)
1999-2003, 湖北师范大学, 学士(生物科学)

 

工作经历:
2018-至今,南方科技大学,研究副教授
2009-2018, 中国科学院深圳先进技术研究院, 助理研究员/副研究员
2017–2018, 香港大学, 访问学者
2006–2007, Morehouse School of Medicine,访问学者

 

科研项目:
2017-2020, 蛋白质类泛素化修饰的单分子检测与成像分析研究,国家自然科学基金面上项目,项目负责人
2016-2019, 中国科学院青年创新促进会会员项目,中国科学院,项目负责人
2011-2013, 动点Mis12 复合物组装动力学及其在染色体分离中功能解析,国家自然科学基金青年科学基金项目,项目负责人
2011-2015, 量子点标记技术研究病毒侵染过程及宿主应答,国家重大科学研究计划,项目骨干

 

获奖情况及荣誉:
深圳市海外高层次人才(孔雀C类),2018
“广东特支计划”青年拔尖人才,2017
广东省科学技术奖二等奖,2017
中国科学院青年创新促进会会员,2015
深圳市高层次人才(后备级),2014
深圳市自然科学奖二等奖,2014

 

代表性论文:
[1] Li Y.Y., Yang Y.,* Zhang C.Y.* Visualization and Quantification of Sortase Activity at the Single-Molecule Level via Transpeptidation-Directed Intramolecular Förster Resonance Energy Transfer. Anal. Chem., 2018, 90, 13007-13012. (Nature Index article, IF=6.042)
[2] Xu A. J., Yang Y.,* Zhang C.Y.* Transpeptidation-directed intramolecular bipartite tetracysteine
display for sortase activity assay. Chem. Commun., 2018, 54, 8116-8119. (Nature Index article, IF=6.29)
[3] Yang Y., Liang Y., Zhang C.Y.* Label-Free and Homogenous Detection of Caspase-3-Like Proteases by Disrupting Homodimerization-Directed Bipartite Tetracysteine Display. Anal. Chem., 2017, 89, 4055-4061. (Nature Index article, IF=6.042)
[4] Zhou J., Yang Y., Zhang C.Y.* Toward Biocompatible Semiconductor Quantum Dots: From Biosynthesis and Bioconjugation to Biomedical Application. Chem. Rev., 2015, 115, 11669-11717. (SCI, IF=52.613).
[5] Wang L. J.,† Yang Y.,† Zhang C.Y.* Phosphorylation-directed assembly of a single quantum dot based nanosensor for protein kinase assay. Anal. Chem., 2015, 87, 4696-4703. (Nature Index article, IF=6.042)
[6] Yang Y., Zhang C.Y.* Visualizing and Quantifying Protein PolySUMOylation at the Single-Molecule Level. Anal. Chem., 2014, 86, 967-972. (Nature Index article, Editors’ Highlight)
[7] Ma F.,† Yang Y.,† Zhang C.Y.* Ultrasensitive Detection of Transcription Factors Using Transcription-Mediated Isothermally Exponential Amplification-Induced Chemiluminescence. Anal. Chem., 2014, 86, 6006-6011. (Nature Index article, IF=6.042)
[8] Yang Y., Zhang C.Y.* Simultaneous measurement of SUMOylation using SNAP/CLIP-tag-mediated translation at the single-molecule level. Angew. Chem. Int. Ed., 2013, 52, 691-694. (Nature Index article, IF=12.102)
[9] Zhou J.,† Yang Y.,† Zhang C.Y.* A low-temperature solid-phase method to synthesize highly
fluorescent carbon nitride dots with tunable emission. Chem. Commun., 2013, 49, 8605-8607. (Nature Index article, Back cover)
[10] Yang Y., Zhang C.Y.* Sensitive Detection of Intracellular Sumoylation via SNAP Tag-Mediated
Translation and RNA Polymerase-Based Amplification. Anal. Chem., 2012, 84, 1229-1234. (Nature
Index article, IF=6.042)
[11] Yang Y., Wu F., Ward T., Yan F., Wu Q., Wang Z.Y., McGlothen T., Peng W., You T. P., Sun M. K., Cui T. X., Hu R. M., Dou Z., Zhu J. D., Xie W., Rao Z. H., Yao X. B.* Phosphorylation of HsMis13 by aurora B is essential for assembly of functional kinetochore. J. Biol. Chem., 2008, 283, 26726-26736.

© 2018 All Rights Reserved. 粤ICP备14051456号