Faculty

WANG Lin
Associate professor
0755-88015573
wangl7@sustech.edu.cn

Personal Profile

Dr. Lin Wang is currently tenured associate professor of Orthopaedic Surgery at School of Medicine, Southern University of Science and Technology (SUSTech), and attending spinal surgeon at International Orthopaedic Center, SUSTech Hospital. Dr. Wang graduated from the Fourth Military Medical University with honors in 2000. He received his surgical internship and orthopaedic surgical residency at Xijing Hospital, where he also completed a pediatric and adult spinal surgery fellowship. He received his M.D. and Ph.D. degree under the supervision of Prof. Yun-yu Hu at PLA institute of orthopaedics, Xijing Hospital, Xi’an, in 2008. He remained at Washington University School of Medicine as a visiting research scholar in 2012, under the tutelage of Dr. Lawrence G. Lenke, president of the Scoliosis Research Society 2010-2011, one of the world's foremost leaders in complex spinal deformity surgery. Dr. Wang remained at Xijing Hospital as an attending spinal surgeon, appointed as supervisor for candidates of master degree in orthopaedic surgery in 2015 and promoted to associated professor in 2016. As an academic spinal surgeon, His research has focus on the precise surgical treatment of pediatric and adult patients with various forms of spinal anomalies, in particular, on such spinal deformities as scoliosis, kyphosis, high-grade spondylolisthesis, and major coronal and sagittal malalignment. Dr. Wang also worked on bioreactor, 3D dynamic cell culture, biological behavior of 3D printed scaffold as bone graft under diabetes conditions, as well as other factors about reconstruction of segmental bone defect in tissue engineering and regenerative medicine field.

 

Research

1. The core mechanism of the steady state imbalance of glycolipid metabolism in the development of osteopathy

2. Microenvironment and biological behavior of the surface interface of bone implanted materials

3. Bone tissue engineering and regenerative medicine

 

Teaching

Introduction of Bone & Joint Disorders

 

Education

1995-2000  Fourth Military Medical University, PLA,  Bachelor of Medicine

2002-2005  PLA Institute of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Master of Orthopaedics

2005-2008  PLA Institute of Orthopaedics, Xijing Hospital, Fourth Military Medical University, MD&Ph.D

2012.1-8 Spinal Surgery Center, Washington University in St. Louis, School of Medicine, Research Fellow

 

Academic Appointments

2000-2008, Residency/Teaching Assistant, Department of Orthopaedic Surgery, Xijing Hospital,Fourth Military Medical University

2008-2016, Attending Surgeon/Instructor, Department of Orthopaedic Surgery, Xijing Hospital,Fourth Military Medical University

2016-2018.7, Attending Surgeon/Associate Professor, Department of Orthopaedic Surgery, the First Affiliated Hospital of Xi’an Jiaotong University

2018.7-Now, Attending Spinal Surgeon/Associate Professor, School of Medicine, Southern University of Science and Technology

 

Peer-reviewed Publications

[1] F. Wang, L. Wang, Y. Feng, X. Yang, Z. Ma, L. Shi, X. Ma, J. Wang, T. Ma, Z. Yang, X. Wen, Y. Zhang, W. Lei, Evaluation of an artificial vertebral body fabricated by a tantalum-coated porous titanium scaffold for lumbar vertebral defect repair in rabbits, Scientific Reports 8(1) (2018) 8927.

[2] X.F. Hu, L. Wang, G. Xiang, W. Lei, Y.F. Feng, Angiogenesis impairment by the NADPH oxidase-triggered oxidative stress at the bone-implant interface: Critical mechanisms and therapeutic targets for implant failure under hyperglycemic conditions in diabetes, Acta biomaterialia 73 (2018) 470-487.

[3] X.-F. Hu, Y.-F. Feng, G. Xiang, W. Lei, L. Wang, Lactic acid of PLGA coating promotes angiogenesis on the interface between porous titanium and diabetic bone, Journal of Materials Chemistry B 6(15) (2018) 2274-2288.

[4] B.B. Zhang, H.R. Tao, T.L. Wu, L. Wang, C.G. Duan, T. Zhang, T. Li, W.Z. Yang, M. Liu, J. Ma, Safety and Efficacy of Single-Stage Surgical Treatment for Congenital Scoliosis Associated with Intraspinal Mass, Sci Rep 7 (2017) 41229.

[5] J. Wang, X.Y. Ma, Y.F. Feng, Z.S. Ma, T.C. Ma, Y. Zhang, X. Li, L. Wang, W. Lei, Magnesium Ions Promote the Biological Behaviour of Rat Calvarial Osteoblasts by Activating the PI3K/Akt Signalling Pathway, Biol Trace Elem Res 179(2) (2017) 284-293.

[6] X.Y. Ma, Y.F. Feng, T.S. Wang, W. Lei, X. Li, D.P. Zhou, X.X. Wen, H.L. Yu, L.B. Xiang, L. Wang, Involvement of FAK-mediated BMP-2/Smad pathway in mediating osteoblast adhesion and differentiation on nano-HA/chitosan composite coated titanium implant under diabetic conditions, Biomater Sci 6(1) (2017) 225-238.

[7] X.F. Hu, L. Wang, Y.Z. Lu, G. Xiang, Z.X. Wu, Y.B. Yan, Y. Zhang, X. Zhao, Y. Zang, L. Shi, W. Lei, Y.F. Feng, Adiponectin improves the osteointegration of titanium implant under diabetic conditions by reversing mitochondrial dysfunction via the AMPK pathway in vivo and in vitro, Acta biomaterialia 61 (2017) 233-248.

[8] L. Wang, X. Hu, X. Ma, Z. Ma, Y. Zhang, Y. Lu, X. Li, W. Lei, Y. Feng, Promotion of osteointegration under diabetic conditions by tantalum coating-based surface modification on 3-dimensional printed porous titanium implants, Colloids Surf B Biointerfaces 148 (2016) 440-452.

[9] Y. Zhang, L. Tian, X. Zhao, Z. Wu, L. Wang, L. Shi, G. Cui, W. Lei, Effect of Preoperative Tracheal Stretch Exercise on Anterior Cervical Spine Surgery: A Retrospective Study, Journal of spinal disorders & techniques 28(10) (2015) E565-70.

[10] L. Wang, X. Zhao, B.Y. Wei, Y. Liu, X.Y. Ma, J. Wang, P.C. Cao, Y. Zhang, Y.B. Yan, W. Lei, Y.F. Feng, Insulin improves osteogenesis of titanium implants under diabetic conditions by inhibiting reactive oxygen species overproduction via the PI3K-Akt pathway, Biochimie 108 (2015) 85-93.

[11] X. Li, X.Y. Ma, Y.F. Feng, L. Wang, C.T. Wang, A novel composite scaffold consisted of porous titanium and chitosan sponge for load-bearing applications: Fabrication, characterization and cellular activity, Composites Science and Technology 117 (2015) 78-84.

[12] X. Li, X.Y. Ma, Y.F. Feng, Z.S. Ma, J. Wang, T.C. Ma, W. Qi, W. Lei, L. Wang, Osseointegration of chitosan coated porous titanium alloy implant by reactive oxygen species-mediated activation of the PI3K/AKT pathway under diabetic conditions, Biomaterials 36 (2015) 44-54.