师资

个人简介:
安俊卿,南方科技大学医学院研究助理教授,2023年获得美国佐治亚州立大学博士学位,2023-2025年于南方科技大学医学院从事博士后研究工作。主要研究方向为心血管疾病的免疫和代谢调控机制。研究工作发表于Cellular&molecular Immunology, Theranostics, Plos Pathogens和 iScience等国际学术期刊。主持国家自然科学基金青年科学基金项目、中国博士后科学基金特别资助(站前)、和中国博士后科学基金面上项目。获批国家资助博士后计划C档。
教育背景:
2017.08-2023.01 佐治亚州立大学,分子与转化医学中心,生物医学科学,博士
2015.09-2017.07 中国农业大学,动物医学院,基础兽医学,硕士
2010.09-2015.07 西北农林科技大学,动物医学院,动物医学,学士
工作经历:
2023.03-2025.02 南方科技大学,医学院,博士后
2025.03-2025.07 南方科技大学,医学院,高级研究学者
2025.07-今 南方科技大学,医学院,研究助理教授
研究领域:
1)动脉粥样硬化的炎症调控机制研究
2)病理性心肌重构的代谢调控机制研究
发表论文:
1) An J#, Ouyang L#, Yu C, Carr SM, Ramprasath T, Liu Z, Song P, Zou MH, DingY. Nicotine exacerbates atherosclerosis and plaque instability via NLRP3 inflammasome activation in vascular smooth muscle cells. Theranostics. 2023 May
2) An J, DingY, Yu C, Li J, You S, Liu Z, Song P*, Zou MH*. AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells. iScience. 2021 Dec
3) An J, Zhao X, Wang Y, Noriega J, Gewirtz AT*, Zou J*. Western-style diet impedes colonization and clearance of Citrobacter rodentium. PLoS Pathog. 2021 Apr
4) Zhu H#, Liu Z#*, An J#, Zhang M, Qiu Y, Zou MH. Activation of AMPKα1 is essential for regulatory T cell function and autoimmune liver disease prevention. Cell Mol Immunol.2021.Dec (co-first author)
5) Li J, Yao H, Zhao F, An J, Wang Q, Mu J, Liu Z, Zou MH, Xie Z. Pycard deficiency inhibits microRNA maturation and prevents neointima formation by promoting chaperone-mediated autophagic degradation of AGO2/argonaute 2 in adipose tissue. Autophagy. 2024 Mar.
6) Cai Z, You S, Liu Z, Song P, Zhao F, An J, DingY, He B, Zou MH. Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo. Cell Death Dis. 2024 Mar 14
7) Song P*, An J, Zou MH. Immune Clearance of Senescent Cells to Combat Ageing and Chronic Diseases. Cells. 2020 Mar 10;9(3):671.
8) DingY, Han Y, Lu Q, An J, Zhu H, Xie Z, Song P, Zou MH. Peroxynitrite-Mediated SIRT (Sirtuin)-1 Inactivation Contributes to Nicotine-Induced Arterial Stiffness in Mice. Arterioscler Thromb Vasc Biol.
9) Han C, Yang J, Zhang E, Jiang Y, Qiao A, Du Y, Zhang Q, An J, Sun J, Wang M, Nguyen T, Lal H, Krishnamurthy P, Zhang J, Qin G. Metabolic labeling of cardiomyocyte-derived small extracellular-vesicle (sEV) miRNAs identifies miR-208a in cardiac regulation of lung gene expression. J Extracell Vesicles. 2022 Oct;11(10):e12246.
10) Tian J, Shi R, Xiao P, Liu T, She R, Wu Q, An J, Hao W, Soomro M. Hepatitis E Virus Induces Brain Injury Probably Associated With Mitochondrial Apoptosis. Front Cell Infect Microbiol. 2019 Dec 20; 9:433.
11)Tian J, Shi R, Liu T, She R, Wu Q, An J, Hao W, Soomro MH. Brain Infection by Hepatitis E Virus Probably via Damage of the Blood-Brain Barrier Due to Alterations of Tight Junction Proteins.Front Cell Infect Microbiol. 2019 Mar 19; 9:52.
12) Wu Q, An J, She R, Shi R, Hao W, Soomro M, Yuan X, Yang J, Wang J. Detection of Genotype 4 Swine Hepatitis E Virus in Systemic Tissues in Cross-Species Infected Rabbits. PLoS One. 2017 Jan 27;12(1):e0171277.
13) An J, Liu T, She R, Wu Q, Tian J, Shi R, Hao W, Ren X, Yang Y, Lu Y, Yang Y, Wu Y. Replication of hepatitis E virus in the ovary and promotion of oocyte apoptosis in rabbits infected with HEV-4. Oncotarget. 2017 Dec 17;9(4):4475-4484.
14) Tang J, Wu Q, Tang X, Shi R, Suo J, Huang G, An J, Wang J, Yang J, Hao W, She R, Suo X. Development of a vivo rabbit ligated intestinal Loop Model for HCMV infection. J Anim Sci Biotechnol. 2016 Dec 13; 7:69.
15)Zhang L, Lu Y, An J, Wu Y, Liu Z, Zou MH. AMPKα2 regulates fasting-induced hyperketonemia by suppressing SCOT ubiquitination and degradation. Sci Rep. 2024 Jan 19;14(1):1713.