师资
董哲，南方科技大学化学系副教授（研究员），博士生导师。2012年本科毕业北京大学, 师从余志祥教授。2012年至2016年，在德州大学奥斯汀分校董广彬教授课题组攻读博士学位。2016年随着课题组一起转入芝加哥大学，并于2018年获得美国芝加哥大学博士学位。同年加入普林斯顿大学2021年化学诺贝尔奖得主有机化学家David Macmillan教授课题组从事博士后工作研究。2020年入选海外高层次人才计划青年项目，2021年加入南方科技大学化学系。2022年获批科技部重点研发专项课题负责人；参与孔雀团队和广创团队。
主要研究方向为：
1.立体专一型的偶联反应：纯烷基手性季碳是有机合成中难点，我们开发了一系列以手性环氧和手性醇为原料的手性季碳构筑方法，高效高选择性地将手性碳氧键转化为了手性碳碳键。首次发展了立体专一型的同面取代反应，丰富了取代反应的类型。
2. 碳正离子与碳负离子的直接取代反应：发展了一系列调控碳正离子活性的新方法来高效构筑季碳
3. 新型生物标记探针的设计合成：开发适用于生物体系近程标记反应的新型多功能探针
荣誉奖励：
2015年获得国家优秀自费留学生奖学金;
2017年入选Reaxy-PHD奖最终名单
2018年获得芝加哥大学优秀博士论文奖;
2020年入选海外高层次人才计划青年项目
近年资助:
2021-2024，海外高层次人才计划青年项目
代表性论文：
2025
24.Synthesis of chiral germanium center enabled by poly-deborylative alkylation and desymmetrization.
Ke Wang, Xin-Yuan Liu & Zhe Dong*,Nature Communications,2025,https://doi.org/10.1038/s41467-025-60397-x
2024
23.Accurate triplet energies prediction method based on the hot-bandmodel.
Wenbin Huang and Zhe Dong*,Chem , 2024,doi.org/10.1016/j.chempr.2024.10.014.
22.Aqueous alkaline phosphate facilitates the nonexchangeable deuteration of peptides and proteins.
Tingting Zhang, Zhixiong Jin, Heng Zhao, Can Lai,Zheyi Liu, Pan Luo,Zhe Dong and Fangjun Wang*.RSC Adv., 2024, 14, 8075,
doi: 10.1039/d3ra08636d
21.Copper-Catalyzed Asymmetric Three-Component Radical 1,2-Carboamination of Acrylamides with Arylamines: Access to Chiral α-Tertiary N-Arylamines.
Jia-Heng Fang†, Ji-Jun Chen†, Xuan-Yi Du†, Zhe Dong†, Run-Yan Tian, Chang-Jiang Yang, Fu-Li Wang,Cheng Luan, Zhong-Liang Li & Xin-Yuan Liu*,CCS Chem. 2024,doi: 10.31635/ccschem.024.202404389.
20.Probing the functional hotspots inside protein hydrophobic pockets by in situ photochemical trifluoromethylation and mass spectrometry.
Can Lai, Zhiyao Tang,Zheyi Liu, Pan Luo, Wenxiang Zhang,Tingting Zhang,Wenhao Zhang,Zhe Dong,*Xinyuan Liu, Xueming Yang and Fangjun Wang*，Chemical Science2024,doi:10.1039/d3sc05106d.
2023
19.Reversible C–H sampling for direct functional group translocation.
Ke Wang and Zhe Dong*Chem Catalysis2023,doi:10.1016/j.checat.2023.100856.
18.Enantioconvergent Cu-catalysed N-alkylation of aliphatic amines.
Ji-Jun Chen, Jia-Heng Fang, Xuan-Yi Du, Jia-Yong Zhang, Jun-Qian Bian, Fu-Li Wang, Cheng Luan, Wei-Long Liu, Ji-Ren Liu, Xiao-Yang Dong, Zhong-Liang Li, Qiang-Shuai Gu, Zhe Dong & Xin-Yuan Liu* Nature 2023,doi.org/10.1038/s41586-023-05950-8
17.Dual-catalyst-enabled olefin 1,2-difunctionalization for a-chloroalkylboronic esters.
Zhe Dong* chem.2023, 9, 8–15，doi:10.1016/j.chempr.2022.12.009.
Prior to SUSTech
16. Metallaphotoredox-enabled deoxygenative arylation of alcohols.
Zhe Dong, David W.C. Macmillan* Nature 2021, doi: 10.1038/s41586-021-03920-6.
15. Compatibility Score for Rational Electrophile Selection in Pd/NBE Cooperative Catalysis.
Xiaotian Qi, Jianchun Wang, Zhe Dong, Guangbin Dong*, Peng Liu* Chem. 2020, 6, 2810.
14. A Mechanistic Analysis of Metallaphotoredox C–N Coupling: Photocatalysis Initiates and Perpetuates Ni(I)/Ni(III) Coupling Activity.
Nicholas A. Till, Lei Tian, Zhe Dong, Gregory Scholes, and David W. C. MacMillan* J. Am. Chem. Soc. 2020, 142, 15830.
13. Modular and Regioselective Synthesis of All-Carbon Tetrasubstituted Olefins Enabled by an Alkenyl Catellani Reaction.
Jianchun Wang, Zhe Dong, Cheng Yang, and Guangbin Dong* Nat. Chem. 2019, 11, 1106.
12. Sulfenamide-Enabled Ortho Thiolation of Aryl Iodides via Palladium/Norbornene Cooperative Catalysis.
Renhe Li, Yun Zhou, Ki-Young Yoon, Zhe Dong* and Guangbin Dong* Nat. Commun. 2019, 10, 3555.
11. Palladium/Norbornene-Catalyzed Indenone Synthesis from Simple Aryl Iodides: Concise Syntheses of Pauciflorol F and Acredinone A.
Feipeng, Liu; Zhe, Dong; Jianchun, Wang; Guangbin, Dong.* Angew. Chem., Int. Ed. 2019, 58, 2144.
10. Complementary Site-Selectivity in Arene Functionalization Enabled by Overcoming the “Ortho Constraint” in the Palladium/Norbornene Catalysis.
Jianchun Wang, Renhe Li, Zhe Dong, Peng Liu and Guangbin Dong* Nat. Chem. 2018, 10, 866.
9. Modular ipso/ortho Difunctionalization of Aryl Bromides via Palladium/Norbornene Cooperative Catalysis.
Zhe Dong, Gang Lu, Jianchun Wang, Peng Liu* and Guangbin Dong* J. Am. Chem. Soc. 2018, 140, 8551.
8. Transition metal catalyzed C-H bond alkylation using alkenes.
Zhe Dong, Zhi Ren, Samuel J. Thompson, Yan Xu and Guangbin Dong* Chem. Rev. 2017, 117, 9333.
7. New Directions in Pd/Norbornene-Catalyzed Activation of Arene C–H Bonds.
Zhe Dong.* Chem. 2016, 1, 520.
6. Reagent-Enabled Ortho Alkoxycarbonylation of Aryl Iodides via Palladium/Norbornene Catalysis
Jianchun, Wang; Lei, Zhang; Zhe Dong;* Guangbin, Dong.* Chem. 2016, 1, 581.
5. Ortho C−H Acylation of Aryl Iodides by Palladium/Norbornene Catalysis.
Zhe, Dong; Jianchun, Wang; Zhi, Ren; Guangbin, Dong.* Angew. Chem., Int. Ed. 2015, 54, 12664.
4. Simple Amine-Directed meta-Selective C−H Arylation via Pd/Norbornene Catalysis.
Zhe, Dong; Jianchun, Wang; Guangbin, Dong.* J. Am. Chem. Soc. 2015, 137, 5887.
3. Ortho vs Ipso: Site-Selective Pd and Norbornene-Catalyzed Arene C–H Amination Using Aryl Halides.
Zhe Dong and Guangbin Dong.* J. Am. Chem. Soc., 2013, 135, 18350.
2. Gold(I)-Catalyzed endo-Selective Intramolecular α-Alkenylation of β-Yne-Furans: Synthesis of Seven-Membered-Ring-Fused Furans and DFT Calculations.
Zhe Dong, Cheng-Hang Liu, Yi Wang, Mu Lin and Zhi-Xiang Yu.* Angew. Chem. Int. Ed. 2013, 52, 14157.
1. α,β-Divinyl Tetrahydropyrroles as Chiral Chain Diene Ligands in Rhodium(I)-Catalyzed Enantioselective Conjugated Additions.
Qian Li, Zhe Dong, and Zhi-Xiang Yu* Org. Lett., 2011, 13, 1122.