刘洪梅，南方科技大学研究副教授、硕士研究生导师。深圳市地方级领军人才、江苏省“六大人才高峰”高层次人才。2015年毕业于中国科学院过程工程研究所，获得理学博士学位。主要从事组织工程和微纳机器人治疗肿瘤的研究工作。在Science Advances、Advanced Materials、ACS Nano、Advanced Functional Materials、Bioactive Materials、Biomaterials、Chemical Engineering Journal、Theranostics等SCI杂志发表论文66篇，其中以第一作者或通讯作者发表学术论文56篇，中国科学院分区一区19篇，H指数29。主持了国家自然科学基金青年项目、江苏省重点研发计划（社会发展）项目和深圳市面上项目等共14项课题。授权12件中国发明专利。担任中国医师协会脑胶质瘤专业委员会药物与生物治疗学组委员、中国抗癌协会会员、中国神经科学学会委员。

教育背景

2001年9月-2005年7月，哈尔滨师范大学，生物学院，本科/学士

2005年9月-2008年7月，东北农业大学，生物学院，研究生/硕士 导师：王学东

2011年9月-2015年1月，中国科学院过程工程研究所，生物化工学院，研究生/博士 导师：张欣

工作经历

2008年8月-2011年8月，吉林医药学院，科技处，助理实验师

2015年4月-2021年6月，徐州医科大学，临床学院，副教授，硕导

2015年9月-2019年3月，徐州医科大学，生物学，博士后，合作导师：于如同

2021年7月-至今，南方科技大学，生物医学工程系，研究副教授

获奖情况及荣誉

1.江苏省科学技术奖一等奖（2020）

2.江苏省医学科技奖一等奖（2020）

3.江苏省教育科学研究成果二等奖（2021）

4.中国医师协会脑胶质瘤委员会颁发的优秀青年科技工作者称号（2018）

研究兴趣

主要从事组织工程修复和微纳机器人治疗肿瘤的研究工作

代表论文

[1] Xuefeng Zhang#, Xuyang Huang#, Diancheng Hang#, Jiaqi Jin, Shanshan Li*, Yufu Zhu*, Hongmei Liu*, Targeting pyroptosis with nanoparticles to alleviate neuroinflammatory for preventing secondary damage following traumatic brain injury，Science Advances, 2024, 10, eadj4260.

[2] Dan Zhou, Wantao Wang, Wenzheng Ma, Yiwen Xian, Zijie Zhang, Zheng Pan, Yixi Li, Lin Huang, Lei Liu, Zhaomin Zheng, Hongmei Liu*, Decheng Wu*. Cartilage-adaptive hydrogels via the synergy strategy of protein templating and mechanical training, Advanced Materials, 2025, 37, 2414081.

[3] Zijie Zhang, Yiwen Xian, Dan Zhou, Yang iu, Chao lu, Wiliam Wella lu,* Hongmei liu* and Decheng Wu*. spider sik inspired Hierarchical filbrousHvdrogels with Extreme Robustness via a Top-Down Multidimensional Engineering Strategy. Advanced Functional Materials 2025, 35, 2420561.

[4] Wenzheng Ma#, Wantao Wang#, Lei Zhao, Jinghao Fan, Lei Liu, Lin Huang, Baogan Peng, Jianru Wang, Baoshan Xu, Hongmei Liu*, Decheng Wu*, Zhaomin Zheng*, Reprogramming to restore youthful epigenetics of senescent nucleus pulposus cells for mitigating intervertebral disc degeneration and alleviating low back pain, Bone Research, 2025,13:35.

[5] Jinjin Chen, Mingkang Liu, Shiyi Chen, C. Perry Chou, Hongmei Liu*, Decheng Wu*, Yilan Liu*. Engineered therapeutic bacteria with enhanced membrane vesicle production for treatment of inflammatory bowel disease in a murine model, ACS Nano, 2025, 19: 2405-2418.

[6] WantaoWang, LeiLiu, WenzhengMa, Lei Zhao, Lin Huang, DanZhou, Jinghao Fan, Jianru Wang, Hongmei Liu*, DechengWu*, Zhaomin Zheng*, Ananti-senescence hydrogel with pH-responsive drug release for mitigating intervertebral disc degeneration and low back pain, Bioactive Materials, 2024, 41, 355-370.

[7] Dan Zhou, Hongmei Liu*, Zhaomin Zheng*, Decheng Wu*, Design principles in mechanically adaptable biomaterials for repairing annulus fibrosus rupture: A review. Bioactive Materials, 2024, 31, 422-439.

[8] Lei Liu#, Yiwen Xian#, Wantao Wang, Lin Huang, Jinghao Fan, Wenzheng Ma, Yixi Li, Hongmei Liu*, Jia-Kuo Yu*, and Decheng Wu*, Meniscus-inspired self-lubricating and friction-responsive hydrogels for protecting articular cartilage and improving exercise, ACS Nano, 2023, 17, 24308-24319.

[9] Lei Liu#, Wantao Wang#, Lin Huang, Yiwen Xian, Wenzheng Ma, Jinghao Fan, Yixi Li, Hongmei Liu*, Zhaomin Zheng*, Decheng Wu*, Injectable pathological microenvironment-responsive anti-inflammatory hydrogels for ameliorating intervertebral disc degeneration, Biomaterials, 2024, 306, 122509.

[10] Yufu Zhu, Jiaqi Jin, Yang Lu, Diancheng Hang, Xuefeng Zhang, Gang Zhao, Qing Wang*, Yuling Li*, Hongmei Liu*. Collagen IV/laminin-1 coated temozolomide-prodrug hydrogel for recruiting and eradicating residual glioma cells, Chemical Engineering Journal, 2025, 503: 0-158616

[11] Yufu Zhu#, Xuefeng Zhang#, Jiaqi Jin#, Xiaoqian Wang#, Yang Liu, Jian Gao, Diancheng Hang, Lin Fang, Hengzhu Zhang*, Hongmei Liu*. Engineered oncolytic virus coated with anti-PD-1 and alendronate for ameliorating intratumoral T cell hypofunction, Experimental Hematology & Oncology, 2025, 14: 16. 

[12] Yuhan Han#, Zhengzhong Han#, Xuyang Huang#, Shanshan Li, Guoliang Jin, Junfeng Feng*, Decheng Wu*, and Hongmei Liu*, An injectable refrigerated hydrogel for inducing local hypothermia and neuroprotection against traumatic brain injury in mice. Journal of Nanobiotechnology, 2024, 251.

[13] Xuefeng Zhang#, Qing Guo#, Zongren Zhao#, Peng Cheng, Anhua Wu*, Hongmei Liu*, Engineering prodrug nanoparticles for targeted therapy in heterogeneous glioblastoma, Chemical Engineering Journal, 2023, 474, 145557.

[14] Zeqi Zhao, Zhengzhong Han, Yudi Shao, Konduru Naveena , Jintao Yuan, Nan Zhou, Caiji Wang, Xuanyi Li, Xi Shi, Dan Jin, Bing Xu, Fuxing Dong , Zhiwei Liu, Wei Li, Hongmei Liu*, Yuehua Qiao*. A OHCs-targeted strategy for PEDF delivery in noise-induced hearing loss, Advanced Healthcare Materials, 2025, 14: 2403537.

[15] Lei Liu#, Wantao Wang#, Lin Huang, Yiwen Xian, Wenzheng Ma, Lei Zhao, Yixi Li, Zhaomin Zheng*, Hongmei Liu*, and Decheng Wu*, Injectable inflammation-responsive hydrogels for microenvironmental regulation of intervertebral disc degeneration, Advanced Healthcare Materials, 2024, e2400717.